Cis-dichlorodiammineplatinum (II) in metastatic soft tissue sarcomas
Karakousis, C.P.; Holtermann, O.A.; Holyoke, E.D.
Cancer Treatment Reports 63(11-12): 2071-2075
1979
ISSN/ISBN: 0361-5960 PMID: 393389 Document Number: 150505
cis-Dichlorodiammineplatinum(II) was given to 13 patients with metastatic sarcomas following failure in two previous chemotherapy protocols. Two of these patients had complete regression which lasted 6 months in one patient and is still present after 8 months in the other. One patient had a greater than 50% regression which lasted 5 months. Three patients had disease stabilization for 2 months each. cis-Dichlorodiammineplatinum(II), as a single agent, was well-tolerated with no significant renal or auditory toxicity.