The bank of biological material in the SU.VI.MAX study
Galan, P.; Favier, A.; Preziosi, P.; Bertrais, S.; Arnault, N.; Hercberg, S.
Revue d'Epidemiologie et de Sante Publique 51(1 Part 2): 147-150
2003
ISSN/ISBN: 0398-7620 PMID: 12684572 Document Number: 558802
The "Supplementation en Vitamines et Mineraux Antioxidants" (SU.VI.MAX) study is a randomized double-blind, placebo-controlled, primary-prevention trial designed to test the efficacy of a daily supplementation with antioxidant vitamins and minerals at nutritional doses, in reducing several major health problems in industrialized countries, and especially the main causes of premature death (cancers and cardiovascular diseases). This 8-year cohort study started in 1994 in France; 13 535 eligible subjects (women aged 35 to 60 years, and men aged 45 to 60 years) were included and were followed up for 8 years. This paper describes conditions and practical aspects for the realization of the biological bank developed on the first sample (1994) and completed in 1996 and 1999. Biological material (buffy coat and plasma samples) are saved and stored at -196 degrees C, -80 degrees C and -20 degrees C for any further tests planned at later date (case-control studies and/or validation of new hypothesis).