Carcinogenic effects of single total-body irradiation with accelerated charged particles and gamma rays
Fedorenko, B.S.; Turusov, V.S.
Voprosy Onkologii 49(5): 615-622
2003
ISSN/ISBN: 0507-3758 PMID: 14682135 Document Number: 553825
The study deals with the frequency of tumorigenesis in the endocrine glands, skin, soft tissues and internal organs of sexually mature female rats, exposed to accelerated charged particles with low LPE, such components of cosmic radiation as 645 MeV and 9 GeV protons and 4 GeV/nuclon ions of helium. The experiment continued until the animals' natural death. We established a high frequency of endocrine and uterine tumors and a comparatively wide range of localizations in rats which had received sufficient doses of gamma radiation. There were no intestinal or renal tumors, while very few tumors of the skin and soft tissues were detected in unexposed animals.