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A study of aspermia-related genes by genchips and analysis of the RAP1A gene

Yang, B.; Gao, X.-K.; Wang, H.; Liu, H.-L.; Chen, B.-Q.; Yuan, J.-L.; Shao, G.-X.; Shao, C.

Zhonghua Nan Ke Xue 9(9): 654-657

2003

ISSN/ISBN: 1009-3591
PMID: 14727349
Document Number: 553421
To study the differential gene expression profiles between the normal and aspermia human testes by genechips. Probes were prepared from mRNA extracted from both normal and aspermia testes and employed on Biostar H-40s genechips to detect the differential gene expression profiles. A distinctly up-regulated gene RAP1A was analyzed by bibliogrphic retrieval. Six hundred and twenty-three differential expressed genes were found, among which the distinctly up-regulated gene RAP1A was closely related to human sperm regulation. Screening the differential gene expression profiles between the normal and aspermia human testes by genechips can be used in the study of aspermia-related genes.

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