Top Abstract Purchase Related
Home
>
Node
>
Subnode

Study of the effect of a short-chain vitamin e analog on the structural and functional state of the plasma membrane of cardiomyocytes in vitro

Donchenko, H.V.; Kuchmenko, O.B.; Mkhitarian, L.S.

Ukrains'kyi Biokhimichnyi Zhurnal 74(5): 66-69

2002

ISSN/ISBN: 0372-3909
PMID: 12916158
Document Number: 551526
The results of study of influence of C6-analog of alpha-tocopherol on the structural and functional state of cardiomyocytes plasma membranes (CPM) in vitro are given. Under condition of incubation of CPM of intact animals the level of phospholipids was decreased, the level of fatty acids was increased, intensity of processes of free-radical oxidation (FRO) was significantly increased and activity of Na+, K(+)-ATPase was decreased in control samples of CPM. The analog of vitamin E supplementation at a concentration of 10 mg/ml of the medium significantly prevented the development of these changes. All of these can be evidence of effective membranes protective action of C6-analog of vitamin E on CPM.

Document emailed within 1 workday
Secure & encrypted payments

Antonenko, L.V.; Kholodova, I.D.; Apukhovskaia, L.I.; Voziian, P.A.; Solodova, E.V.; Kvashnina, L.V. 1990: Structural-functional changes in plasma lipoproteins during vitamin D-deficient rickets in children Ukrainskii Biokhimicheskii Zhurnal 62(3): 54-59
Callari, D.; Cicero, R.; Sichel, G.; Abate, G.; Billitteri, A. 1978: Effect of vitamin D and vitamin e on the erythrocyte membrane. I. Effect on in vitro osmolar resistance and lysis Acta Vitaminologica et Enzymologica 32(1-4): 21-31
Voloshchuk, O.N.; Kopylchuk, G.P. 2015: Peculiarities of the Structural-Functional State of the Cytochrome Part of Liver Mitochondrial Respiratory Chain under Conditions of Acetaminophen-induced Hepatitis against the Background of Alimentary Deprivation of Protein Biofizika 60(3): 519-524
Kalandarov, S.; Bychkov, V.P.; Sergienko, A.V. 1979: Effect of sealed chamber conditions on the functional state of the human adrenal cortex (based on data from a study of the 11-hydroxycortico-steroid content in the blood plasma) Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 13(4): 39-42
Bednarski, P.J.; Kratochwil, N.A.; Otto, A.M. 1994: Reversible and irreversible interactions of a cisplatin analog bearing a 1,2-diphenylethylenediamine ligand with plasma and plasma proteins in vitro Drug Metabolism and Disposition: the Biological Fate of Chemicals 22(3): 419-427
Semenykhina, O.M.; Strutyns'ka, N.A.; Bud'ko, A.I.; Vavilova, H.L.; Sahach, V.F. 2013: Effect of hydrogen sulfide donor NaHs on the functional state of the respiratory chain of the rat heart mitochondria Fiziolohichnyi Zhurnal 59(2): 9-17
Chernousov, M.A.; Metsis, M.L.; Glukhova, M.A.; Antonov, A.S.; Orekhov, A.N. 1984: Study of the structural and functional properties of fibronectin--a high molecular weight plasma glycoproteins--by using monoclonal antibodies Molekuliarnaia Biologiia 18(3): 643-652
Fetisova, L.V.; Azhigirova, M.A.; Viazova, E.P.; Zaĭnalov, A.M.; Khachatur'ian, A.A. 1983: Effect of plasma substitutes on the functional characteristics of the blood in vitro Gematologiia i Transfuziologiia 28(3): 37-39
Kiselevich, A.G. 1972: Effect of pangamic acid (vitamin B 15) on the functional state of the thyroid gland of rats during a dietary deficiency of iodine Voprosy Pitaniia 31(3): 93-94
Bondarev, I.M.; Tregubov, I.G.; Klebanova, A.A. 1974: Effect of vitamin B6 on the blood isoniazid concentration and its role in the regulation of the functional state of central nervous system in dogs Problemy Tuberkuleza 65(4): 73-77
Scott, R.E.; Maercklein, P.B. 1980: Effect of dithiothreitol on plasma membrane intramembranous particle topography in BALB/c 3T3 and simian virus-transformed 3T3 cells and plasma membrane vesicles Journal of the National Cancer Institute 65(2): 415-419
Silver, J.; Ferrone, S. 1979: Structural organization of human DR antigens and their murine analog, I-E antigens: serologic, genetic, and functional implications Transplantation Proceedings 11(4): 1743-1744
Hsia, Y.E.; Lilljeqvist, A.C.; Rosenberg, L.E. 1970: Vitamin B12-dependent methylmalonicaciduria: amino acid toxicity, long chain ketonuria, and protective effect of vitamin B12 Pediatrics 46(4): 497-507
Montet, J.C.; Laperche, Y.; Gérolami, A. 1983: Effect of glycodihydrofusidate, a structural analog of bile salts, on the hepatic transport of bromosulfophthalein in rats Gastroenterologie Clinique et Biologique 7(10): 770-776
Khalfoun, B.; Degenne, D.; Crouzat-Reynes, G.; Bardos, P. 1986: Effect of human syncytiotrophoblast plasma membrane-soluble extracts on in vitro mitogen-induced lymphocyte proliferation. a possible inhibition mechanism involving the transferrin receptor Journal of Immunology 137(4): 1187-1193
Cherrington, C.A.; Hinton, M.; Pearson, G.R.; Chopra, I. 1991: Short-chain organic acids at ph 5.0 kill Escherichia coli and Salmonella spp. without causing membrane perturbation Journal of Applied Bacteriology 70(2): 161-165
Gubskiĭ, I.I.; Levitskiĭ, E.L.; Primak, R.G. 1992: Change in the structural state of fractionated liver chromatin in E vitamin deficiency Ukrainskii Biokhimicheskii Zhurnal 64(5): 86-89
David-Dufilho, M.; Koutouzov, S.; Marche, P.; Pernollet, M.G.; Le Quan Sang, H.; de Mendonça, M.; Grichois, M.L.; Meyer, P.; Devynck, M.A. 1986: Structural and functional alterations of the cell membrane in the prehypertensive rat of the Okamoto Aoki strain Journal of Hypertension. Suppl: Official Journal of the International Society of Hypertension 4(3): S263-S265
Shvinka, N.E.; Caffier, G.; Malev, V.V.; Ryzhova, E.V. 1985: Effect of temperature on the interaction of gramicidin a and its dimer analog with the muscle fiber membrane Biofizika 30(4): 625-631
Nahibin, V.S.; Dosenko, V.Ie.; Pyvovar, S.M.; Moĭbenko, O.O.; Iahupol's'kyĭ, L.M. 2004: Fluorine-containing analog of diazoxide prevented apoptosis in neonatal cardiomyocytes during anoxia-reoxygenation Fiziolohichnyi Zhurnal 50(3): 3-8