Convulsive status secondary to star anise poisoning in a neonate
Gil Campos, M.; Pérez Navero, J.L.; Ibarra De La Rosa, I.
Anales Espanoles de Pediatria 57(4): 366-368
2002
ISSN/ISBN: 0302-4342 PMID: 12392673 Document Number: 549147
Despite its potential toxicity, the use of star anise infusions for the treatment of infant colic is firmly rooted in our culture. In the past year, several cases of infants with acute neurological and gastrointestinal symptoms related to the ingestion of large quantities of star-shaped anise have been reported in Spain. The case of a one-month-old girl admitted to the emergency room with convulsive status after ingesting a considerable amount of star anise administered to relieve possible infant colic is reported. Three repeat doses of diazepam to control the seizures is administered. Because no abnormalities are found and the outcome is favourable without anticonvulsant therapy, the clinical symptoms can be attributed to star anise ingestion, which contains potent neurotoxins as veranisatins. The aetiopathogens and star anise toxicity are discussed and the need for the regulation of natural products with pharmacological effects, which are freely dispensed from drug stores, is stressed. Finally, the regulations of the Ministry of Health and Consumption for 2001 concerning the withdrawal of all anise-consuming products are presented.