An improved method for rapid ABO genotyping

Vanĕk, D.; Pospísek, M.

Sbornik Lekarsky 103(1): 29-33

2002


ISSN/ISBN: 0036-5327
PMID: 12448935
Document Number: 547129
A method for ABO genotyping originally designed by Lee and Chang [3] and further developed by Akane et al. [7] has been even more simplified and improved. We obtained a rapid, robust, sensitive and low cost method for detection of sequence polymorphism of ABO glycosyltransferase gene by changing the MaeII restriction enzyme for its isoschizomer TaiI and by optimization of the condition during digestion and electrophoretic separation.

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