Application of ABO genotyping using polymerase chain reaction method to assess engraftment in bone marrow transplantation--a case report

Chang, C.S.; Lin, S.F.; Lee, J.C.; Chang, J.G.; Liu, T.C.; Huang, S.M.; Chen, T.P.; Liu, H.W.

Gaoxiong Yi Xue Ke Xue Za Zhi 11(10): 574-577

1995


ISSN/ISBN: 0257-5655
PMID: 7494238
Document Number: 447625
We described a case of acute promyelocytic leukemia with O blood type who received bone marrow transplantation during a second remission from his HLA identical, B blood type sibling. Using PCR genotyping of the ABO group and analysis of the variable number of tandem repeats of the D1S80 locus, we could quickly document the successful early engraftment in this patient. We emphasize that the use of PCR ABO genotyping is a quick and valuable method which could be applied to assess the engraftment and its follow up in those transplant cases with donors of mismatched blood groups.

Document emailed within 1 workday
Secure & encrypted payments