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Effect of novelty and behavioral stereotype on development of amnesia in mice

Dubrovina, N.I.; Loskutova, L.V.

Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 88(5): 589-595

2002

ISSN/ISBN: 0869-8139
PMID: 12136726
Document Number: 540968
The research was aimed at analysis of interaction of basic behavioural strategy, extinction of information novelty and efficiency of amnesic influence. It is shown that preliminary habituation to the task apparatus prevented development of amnesia, induced detention of the animal in a dangerous compartment in submissive rather than aggressive mice C57BL/6J. The findings suggest that revealed distinctions in effects of pre-exposure on development of amnesia are essentially predetermined by selectivity of extinction of the information novelty specific to a stereotype of behaviour.

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