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Splenectomy in a patient with beta thalassemia intermedia and severe hemolytic anemia

Pérez, J.A.; Padilla, J.; Rodríguez, M.A.; Cura, S.; Sánchez, S.; Cutillas, M.J.; Sanz, J.

Revista Espanola de Anestesiologia y Reanimacion 48(6): 288-291

2001

ISSN/ISBN: 0034-9356
PMID: 11446945
Document Number: 539133
A 36-year-old woman with beta thalassemia intermedia suffered a hemolytic crisis secondary to Epstein-Barr virus infection. She was given a transfusion of phenotypically compatible blood. However, severe hemolysis persisted (with hemoglobin levels around 4 g/dl) in spite of gamma globulin and corticosteroid administration. Emergency therapeutic splenectomy was performed. We discuss intraoperative management in situations of severe anemia, concluding that it is possible to survive significant decreases in hemoglobin concentration with cardiocirculatory reserve and respiration intact, maintaining normal volume.

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