Autoimmune hemolytic anemia complicating homozygotic beta- thalassemia
Fonty, E.; Cartron, J.; Gire, R.; Girot, R.
Archives Francaises de Pediatrie 43(4): 261-262
1986
ISSN/ISBN: 0003-9764 PMID: 3767588 Document Number: 284832
Four cases of auto-immune hemolytic anemia complicating the course of intermediate or major beta-thalassemia syndromes are reported in children. Ages ranged from 2 to 13 years. Two children had undergone a splenectomy. The direct Coombs test was positive of the IgG +/- complement or complement alone type. Corticosteroid therapy was beneficial in the 3 children who were given this treatment. Coombs test became negative after intervals ranging from 15 days to 8 months.