Timing of analog research in medicinal chemistry
Fischer, J.; Gere, A.
Die Pharmazie 56(9): 675-682
2001
ISSN/ISBN: 0031-7144 PMID: 11593984 Document Number: 538785
Analog research plays an important role in medicinal chemistry. Having identified a new target in molecular biology many similar lead compounds are synthesized resulting in closely related products on the market. Another approach is the further optimising of an existing drug in order to improve on the original. In some cases these two approaches overlap. The question of timing and the importance of analog research are analyzed in this paper.