Endothelium as a pharmacological target
D'Alessio, P.
Current Opinion in Investigational Drugs 2(12): 1720-1724
2001
ISSN/ISBN: 1472-4472 PMID: 11892934 Document Number: 536074
Over the last few years, the increasing knowledge of the endothelium has highlighted its integral role in a number of pathologies. Endothelial cells are pivotally involved in the recruitment and adhesion of leukocytes and platelets, and they express adhesion molecules and growth factors. This review highlights the recent advances made in the understanding of the endothelium and discusses the endothelium as a potential target in a variety of diseases, including cardiovascular diseases, cancer and inflammatory diseases.
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