Outcome of antibiotic therapy in patients with hemorrhagic fever with renal syndrome
Sidel'nikov, I.N.; Martynenko, A.I.
Terapevticheskii Arkhiv 73(11): 78-81
2001
ISSN/ISBN: 0040-3660 PMID: 11806215 Document Number: 535828
To evaluate effects of antibiotics in the treatment of hemorrhagic fever with renal syndrome (HFRS). Clinico-laboratory comparisons were conducted in patients with HFRS who received antibiotics (n = 153) and did not (n = 104) in combined treatment of their disease. HFRS patients treated with antibiotics had weakness, poor appetite, hyperemia of the face, enanthema, hemorrhagic eruption, coated tongue, abdominal distention, thirst, xerostomia, oligoanuria, polyuria significantly longer. Antibiotics raise blood levels of urea and creatinine, urinary levels of protein, ESR, later normalization of renal function, number of plasmic cells and eosinophils, etc. This study evidently shows a negative influence of antibiotics on the course of hemorrhagic fever with renal syndrome.