Top Abstract Purchase Related
Home
>
Node
>
Subnode

Some biological properties of virus strains isolated from hemorrhagic fever patients with renal syndrome

Zhu, G.F.; Li, Z.D.; Li, D.R.; Hong, S.F.; Yu, C.Z.; Song, G.C.; He, J.F.; Pan, C.H.

Chinese Medical Journal 99(8): 653-656

1986

ISSN/ISBN: 0366-6999
PMID: 2879712
Document Number: 272896
The sensitivity of various cell lines and suckling mice to virus strains of hemorrhagic fever with renal syndrome (HFRS) isolated directly from patients' sera was examined. Vero-E6 cells were the most sensitive of all the cell lines tested. Suckling mice, inoculated intracerebrally and intraperitoneally with this virus, became ill about 2 weeks after inoculation. Pathological studies revealed various changes in many organs. Using indirect immunofluorescent and immunoenzymatic staining, viral antigens were found in the sections of the brain, kidenys and lungs. The viruses could be isolated and specific antibodies detected from the same infected mice. By repeated passages of the cell cultures and suckling mice, the virus particles and related structures were observed by electron microscopy in the infected cells.

Document emailed within 1 workday
Secure & encrypted payments

Slonova, R.A.; Astakhova, T.I.; Tkachenko, E.A.; Dzagurova, T.K.; Pavlenko, O.V. 1986: Isolation of strains of the virus of hemorrhagic fever with renal syndrome in a cell culture from human patients and rodents Voprosy Virusologii 31(2): 180-183
Shen, K.Q. 1993: Detection of hemorrhagic fever virus-RNA in renal tissue and peripheral blood in patients with hemorrhagic fever with renal syndrome Zhonghua Yi Xue Za Zhi 73(10): 609
Petrova, I.D.; Seregin, S.V.; Petrov, V.S.; Vyshemirskiĭ, O.I.; Kuzina, I.I.; L'vov, D.K.; Samokhvalov, E.I.; Tiunikov, G.I.; Gutorov, V.V.; Iashina, L.N.; Netesov, S.V. 2003: Genetic characteristics of the S-segment of RNA from two strains of the Crimean-Congo hemorrhagic fever virus isolated in the south of Russia and in Uzbekistan Voprosy Virusologii 48(2): 8-11
Korchanova, N.L.; Simanovskaya, V.K.; Sominina, A.A.; Gordon, M.A.; Goloveshkina, T.N.; Kuznetsova, E.V. 1983: Comparative studies on influenza B virus. I. Biological properties and polypeptide composition of strains isolated in different years Acta Virologica 27(5): 377-384
Lobodzińska, M.; Chomik, M.; Albin, M.; Zakstelskaya, L.Y.; Shenderovich, S.F.; Molibog, E.V. 1983: Comparison of biological properties of A(H1N1) influenza virus strains isolated in 1947 and during the epidemic of 1977 Archivum Immunologiae et Therapiae Experimentalis 31(1): 85-91
Tkachenko, E.A.; Ryl'tseva, E.V.; Miasnikov, I.A.; Ivanov, A.P.; Rezapkin, G.V. 1987: Circulation of the virus of hemorrhagic fever with renal syndrome among small mammals in the territory of the USSR Voprosy Virusologii 32(6): 709-715
Donets, M.A.; Rezapkin, G.V.; Korolev, M.B.; Tkachenko, E.A. 1983: Virus--the causative agent of hemorrhagic fever with renal syndrome--a new representative of the family Bunyaviridae Voprosy Virusologii 3: 330-333
Yan, Y.C. 1983: Characteristics of Xinjiang hemorrhagic fever virus. II. Physicochemical properties of Xinjiang hemorrhagic fever virus Zhonghua Liu Xing Bing Xue Za Zhi 4(3): 132-134
Miasnikov, I.A.; Tkachenko, E.A.; Stepanenko, A.G.; Nurgaleeva, R.G.; Kireev, S.G.; Malkin, A.E. 1992: The intensity of the immune response to the hemorrhagic fever with renal syndrome virus among different population groups of Bashkortostan Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2: 47-50
Tsyganenko, A.I.; Dnestranskaia, L.I.; Gabysheva, L.S. 1990: The biological properties of Staphylococcus aureus and Pseudomonas aeruginosa strains isolated from surgical patients Mikrobiolohichnyi Zhurnal 52(3): 20-23
Davidovich, I.M. 1989: Morphology and aggregative properties of erythrocytes in patients with hemorrhagic fever with nephrotic syndrome Terapevticheskii Arkhiv 61(2): 70-72
Kambaratov, P.I. 1973: Diagnosis of Q fever (Q fever, brucellosis, hemorrhagic fever with renal syndrome and leptospirosis) Sovetskaia Meditsina 36(5): 59-63
Sirotin, B.Z.; Shapiro, I.A.; Maneshin, V.N. 1989: Tubulointerstitial changes in patients with a history of hemorrhagic fever with renal syndrome Terapevticheskii Arkhiv 61(12): 91-95
Sidel'nikov, I.N. 1995: The antibiotic therapy of patients with hemorrhagic fever with renal syndrome Klinicheskaia Meditsina 73(3): 47-48
Ivanov, K.S.; Koshil', O.I.; Petrushko, I.M.; Kapustin, V.M. 1992: The use of reaferon in the combined therapy of patients with hemorrhagic fever with renal syndrome Voenno-Meditsinskii Zhurnal 12: 46-47
Sidel'nikov, I.N.; Sivoraksha, G.A. 1996: Serotonin concentration in the blood of patients with hemorrhagic fever with renal syndrome Klinicheskaia Laboratornaia Diagnostika 1996(5): 21-22
Sidel'nikov, I.N.; Martynenko, A.I. 2001: Outcome of antibiotic therapy in patients with hemorrhagic fever with renal syndrome Terapevticheskii Arkhiv 73(11): 78-81
Khasanova, G.M.; Tutelyan, A.V.; Khasanova, A.N. 2015: Actual nutrition of patients suffered from hemorrhagic fever with renal syndrome Voprosy Pitaniia 84(6): 58-62
Koval'skii, G.S. 1970: Organization of the principles of treatment in patients with hemorrhagic fever with renal syndrome Sovetskaia Meditsina 33(2): 131-134
Zagidullin, I.M.; Sakaeva, M.F. 1983: Hemodialysis in patients with acute renal insufficiency in hemorrhagic fever with nephrotic syndrome Klinicheskaia Meditsina 61(8): 105-107