Gastrointestinal tolerance to a new macrocrystalline form of nitrofurantoin: a collaborative study

Hailey, F.J.; Glascock, H.W.

Current Therapeutic Research 9(12): 600-605

1967


ISSN/ISBN: 0011-393X
PMID: 4965454
Document Number: 5352
In a collaborative study involving 23 investigators and a total of 399 patients, a new macrocrystalline form of nitrofurantoin evoked gastrointestinal intolerance reactions much less frequently than the tablets of this drug now marketed, in patients with known history of nitrofurantoin intolerance. The new form is as effective as the currently available form, by commonly accepted clinical and biologic criteria.

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Gastrointestinal tolerance to a new macrocrystalline form of nitrofurantoin: a collaborative study