Mechanism of alcohol action on gastric secretion
Vasilevskaia, L.S.; Skurikhin, I.M.; Guliev, R.R.
Voprosy Pitaniia 70(3): 9-11
2001
ISSN/ISBN: 0042-8833 PMID: 11517692 Document Number: 534194
In chronic experiment on dogs (3 dogs with Pavlov's miniature stomach, 3 dogs with Heidenhain's miniature stomach) the mechanism of action of alcohol (8%-150 ml) on gastric secretion was clarified. For this purpose the new inhibitor of gastric secretion--glycopeptide was utilized, which action was preset in laboratory of G.K. Shlygin. Was shown, that in effect of alcohol on gastric secretion take place the complicated mechanism including as a nervous regulation (vagus nerves), and humoral: participation of gastrin and histamine in secretory effect of a stomach, and also immediate effect of ethanol on acid glands.