Long-acting beta 2-stimulants
Tamura, G.
Nihon Rinsho. Japanese Journal of Clinical Medicine 59(10): 1973-1978
2001
ISSN/ISBN: 0047-1852 PMID: 11676141 Document Number: 533606
Although inhaled salmeterol and formoterol have been clinically used as long-acting beta 2-stimulants in the world, only tulobuterol tape has been used as long-acting beta 2-stimulants in Japan. When both inhaled agents are used twice daily and the tape is done once daily, it has been reported to achieve stable bronchodilatation for 24 hours. Therefore, these agents are recognized as controllers for asthma therapy. Although tolerance of regular use of salmeterol and formoterol has been reported, it is estimated to be clinically negligible because of small degree. In this review, I described clinical usefulness of long-term treatment of asthma with tulobuterol tape.