Active immune-prophylaxis after allogeneic hematopoietic progenitor cell transplantation in pediatric patients
Ortín De Miguel, M.; Bureo Dacal, E.; Bonilla Miera, C.; Lozano De La Torre, M.J.; Zubizarreta Ypiña, A.
Anales Espanoles de Pediatria 55(1): 39-44
2001
ISSN/ISBN: 0302-4342 PMID: 11412466 Document Number: 531446
There is considerable evidence supporting the disappearance of immunity against diseases for which there is active immune-prophylaxis available after allogeneic hematopoietic progenitor cell transplantation. These findings do not constitute merely an epidemiologic problem. From a strictly clinical point of view, these patients might benefit from the administration of different forms of vaccines against diseases to which they are particularly susceptible. There are, however, no unified criteria for the revaccination of these patients. Moreover, several surveys suggest that active immune-prophylaxis is frequently undervalued in these patients. In the present review, we provide up-to-date information on current trends as well as practical guidelines for the re-immunization of these patients in our environment.