Dynamics of instrumental reflex changes following transection of the corticospinal tract and ablation of the cerebral cortex sensorimotor region in rats
Fanardzhian, V.V.; Gevorkian, O.V.; Mallina, R.K.; Melik-Musian, A.B.; Meliksetian, I.B.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 87(2): 145-154
2001
ISSN/ISBN: 0869-8139 PMID: 11296701 Document Number: 531215
Unilateral transection of bulbar pyramid performed prior to ablation of the ipsilateral sensomotor cortex was shown to facilitate recovery of operant conditioning and compensatory processes in rats. There was no such corticofugal plasticity in ablation of the sensomotor cortex alone. The phenomenon may be explained by switching of descending influences on the cortico-rubrospinal system through participation of the loop: corticorubral projection--red nucleus--inferior olive--cerebellum--thalamus--cerebral cortex.