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Action of cortical extracts of the left and right hemispheres on the recovery of conditioned reflex activity in rats after unilateral removal of the frontal cortex

Kryzhanovskiĭ, G.N.; Romanova, G.A.; Sovetov, A.N.; Lutsenko, V.K.; Karganov, M.Iu.

Biulleten' Eksperimental'noi Biologii i Meditsiny 105(3): 267-270

1988

ISSN/ISBN: 0365-9615
PMID: 3349162
Document Number: 311438
The recovery of active avoidance conditioned reflex (AACR) was investigated after unilateral frontal cortex extirpation. Intraperitoneal injection of extracts from left or right brain cortex (1 mg/kg) of healthy rats (LE or RE) stimulated AACR recovery in animals with lobectomy on the same side. If RE was extracted 9 days after left side brain extirpation, i.e. during the period of the development of compensatory processes, its effect on AACR recovery was stronger in left-operated animals, while in right-operated animals it remained unchanged.

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