Myeloid natural killer cell leukemia resembling a variant of acute promyelocytic leukemia
Burgaleta, C.; de Miguel, D.; López Rubio, M.; Krsnik, I.; Garcia Suárez, J.
Haematologica 86(7): 765-766
2001
ISSN/ISBN: 0390-6078 PMID: 11454535 Document Number: 529305
We report a new case of myeloid/natural killer cell acute leukemia (myeloid/NK). Blast morphology and immunophenotype were similar to a variant of promyelocytic leukemia, resistant to ATRA (acute promyelocytic leukemia with zinc finger-RARalpha fusion). The karyotype was normal and cells did not present RAR-alpha rearrangement. Genetic studies are essential for diagnosis.
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