Report of isolations of unusual lyssaviruses (rabies and Mokola virus) identified retrospectively from Zimbabwe
Bingham, J.; Javangwe, S.; Sabeta, C.T.; Wandeler, A.I.; Nel, L.H.
Journal of the South African Veterinary Association 72(2): 92-94
2001
ISSN/ISBN: 1019-9128 PMID: 11513267 Document Number: 529251
Rabies isolates that had been stored between 1983 and 1997 were examined with a panel of anti-lyssavirus nucleocapsid monoclonal antibodies. Out of 56 isolates from cats and various wild carnivore species, 1 isolate of Mokola virus and 5 other non-typical rabies viruses were identified. The Mokola virus isolate was diagnosed as rabies in 1993 from a cat. Genetic analysis of this isolate suggests that it falls in a distinct subgroup of the Mokola virus genotype. The 5 non-typical rabies viruses were isolated from honey badgers (Mellivora capensis), African civets (Civettictis civetta) and an unidentified mongoose (Herpestidae). These isolates are representatives of rarely-reported wildlife-associated strains of rabies, probably maintained by the slender mongoose (Galerella sanguinea). These findings indicate that both Mokola virus and the mongoose-associated variant may be more common in Zimbabwe than is apparent from routine surveillance.