Efficacy and safety of loratadine vs terfenadine in the treatment of children with perennial allergic rhinitis. Capacity for inhibiting the positive cutaneous response after antihistaminic treatment
Canseco Villarreal, J.I.
Revista Alergia Mexico 42(2): 28-31
1995
ISSN/ISBN: 0002-5151 PMID: 7542992 Document Number: 5243
We studied 104 medical student from the UANL with symptoms of Perennial Allergic Rhinitis, including only 30 patients for this study; seven patients with Loratadine 10 mg, eight with Loratadine 20 mg, and 15 with Terfenadine 120 mg/day/21 days, 20 mg of Loratadine and 120 mg of Terfenadine demonstrated significant decrease of the symptoms (P > 0.005). Two patients had collateral effects with Terfenadine, but Terfenadine were more effective than the Loratadine in the reduction of the skin reactivity.
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