Multicenter, double-blind, placebo-controlled trial of triamcinolone acetonide nasal aerosol in the treatment of perennial allergic rhinitis
Spector, S.; Bronsky, E.; Chervinsky, P.; Lotner, G.; Koepke, J.; Selner, J.; Pearlman, D.; Tinkelman, D.; Weakley, S.; Alderfer, V.
Annals of Allergy 64(3): 300-305
1990
ISSN/ISBN: 0003-4738 PMID: 2178497 Document Number: 359968
In a double-blind study involving 205 patients with perennial allergic rhinitis, statistically significantly greater symptomatic improvements were evident following the administration of 200 micrograms/day triamcinolone acetonide aerosol than following placebo. These improvements were evident as early as week 1 and were sustained throughout the 12-week study. They were accompanied by greater reductions in nasal eosinophils. Triamcinolone acetonide aerosol was well tolerated and had no effect on serum cortisol levels.
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