A case of mediastinal non seminomatous germ cell tumor successfully treated with chemotherapy and curative surgery
Watanabe, A.; Sasaki, A.; Iwaki, H.; Nakashima, S.; Abe, T.
Kyobu Geka. Japanese Journal of Thoracic Surgery 53(12): 1052-1054
2000
ISSN/ISBN: 0021-5252 PMID: 11079315 Document Number: 523439
A 15-year-old male was admitted to our hospital because of left lateral chest pain. Chest XP and CT scan revealed a huge anterior mediastinal mass (13 x 8 x 12 cm). The serum AFP level was raised (8,089 ng/ml). Examination of a percutaneous biopsy of the tumor suggested non-seminomatous germ cell carcinoma. After three courses of chemotherapy with CDDP, Bleomycin and VP-16, the mass reduced in size and the serum AFP level decreased to the normal range. The tumor was completely removed. The postoperative course was uneventful and he has had no recurrence for 10 months following the operation. AFP is a very useful parameter for deciding the timing for an operation.