Interaction of certain RNAases and mannose-specific lectins
Miroshnichenko, O.S.
Ukrains'kyi Biokhimichnyi Zhurnal 72(1): 51-55
2000
ISSN/ISBN: 0372-3909 PMID: 10979559 Document Number: 523069
While defining and elaborating the approaches to examination of the interaction between C-mannosylated tryptophan, recently discovered in the laboratory of Dr. Jan Hofsteenge, and Man/Glc specific lectins the unexpected results were obtained. Some animal origin mannosyl-containing RNases (as was expected) as well as analogous but nonglycosylated recombinant proteins expressed in E. coli (a negative control) were recognized by the mentioned lectins. Protein-protein interactions between lectins and expressed in E. coli nonglycosylated RNases are supposed and require further investigations.