Recording of blood pressure, heart rate and aortic nerve activity during parabolic flight in the rat via radio-telemetry
Waki, H.; Shimizu, T.; Katahira, K.; Nagayama, T.; Yamasaki, M.; Katsuda, S.I.; Wago, H.; Okouchi, T.
Journal of Gravitational Physiology a Journal of the International Society for Gravitational Physiology 7(2): P169-P170
2000
ISSN/ISBN: 1077-9248 PMID: 12697519 Document Number: 517253
Exposure to microgravity induces cardiovascular deconditioning characterized by orthostatic hypotension when astronauts return to the earth. In order to understand the mechanism of cardiovascular deconditioning, it is necessary to clarify the changes in hemodynamics and the cardiovascular regulation system over the period of space flight. The telemetry system applied to freely moving animals will be a useful and appropriate technique for this kind of long term study of the cardiovascular system in the conscious animal during space flight. The purpose of the present study is twofold: firstly, to observe the detailed changes of arterial pressure and heart rate (HR) during microgravity elicited by the parabolic flight in order to study the acute effect of microgravity exposure on the cardiovascular system; and secondly, to test the feasibility of the telemetry system for recording blood pressure, HR and autonomic nervous activities continuously during space flight.