Neoformed multiple hepatic angiomas after exposure to vinyl chloride monomer: report of a case
Borchini, R.; Riboldi, L.; Chiappino, G.
La Medicina del Lavoro 91(3): 251-254
2000
ISSN/ISBN: 0025-7818 PMID: 10965672 Document Number: 516331
The paper describes the case of a 60 years old man with previous protracted exposure to CVM. After a latency of 20 years, the man developed two hepatic hemangiomas, one characterized by rapid growth (4 cm of diameter in 1 year) and surgically removed. On the basis of the anamnestic data (15 years in a PVC polymerization factory in the reactor vessels department) considering the degree and duration of exposure to CVM, an occupational origin of the hepatic hemangiomas is probable. The ability of CVM to induce sclerosis, necrosis and endothelial hyperplasy in the liver tissue may represent the primum movens of hemangiomas.