Karyotype refinement in five patients with acute myeloid leukemia using spectral karyotyping
Calabrese, G.; Fantasia, D.; Spadano, A.; Morizio, E.; Di Bartolomeo, P.; Palka, G.
Haematologica 85(11): 1219-1221
2000
ISSN/ISBN: 0390-6078 PMID: 11064476 Document Number: 513108
Five patients with acute myeloid leukemia showing several complex rearrangements were examined by spectral karyotype (SKY) analysis. Twenty rearrangements, misclassified or undetected by standard cytogenetic techniques, were identified. The present study supports the ability of SKY to detect the organization of chromosome rearrangements and to identify new prognostic markers.
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