Reduced nociceptive responses in mice with alloxan induced hyperglycemia after garlic (Allium sativum Linn.) treatment
Kumar, G.R.; Reddy, K.P.
Indian Journal of Experimental Biology 37(7): 662-666
1999
ISSN/ISBN: 0019-5189 PMID: 10522154 Document Number: 511204
Administration of the ethanol extract of A. sativum bulbs (45 mg/kg, p.o., for for 28 days) to alloxan-induced diabetic mice significantly lowered the serum glucose levels, and reduced nociceptive responses in the tail-flick, hot plate, allodynia, formalin and formalin-induced paw oedema tests. The reversal of hyperglycaemia and hyperalgesia was progressive and more effective as the duration of extract administration increased.
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