Effects of percutaneous liver biopsy in alpacas and llamas
Anderson, D.E.; Silveira, F.
American Journal of Veterinary Research 60(11): 1423-1425
1999
ISSN/ISBN: 0002-9645 PMID: 10566820 Document Number: 510850
Five llamas and 10 alpacas were used to determine changes in selected serum biochemical tests after a single percutaneous liver biopsy and changes in haematological and selected serum biochemical tests after multiple percutaneous liver biopsies. A single percutaneous liver biopsy was performed in 5 llamas and 6 alpacas. Blood samples were collected before and 1, 2 and 3 days after liver biopsy, and submitted for serum biochemical analysis. In the other 4 alpacas, liver biopsy was performed on day 0 and then weekly for 4 weeks. Blood samples were collected at the time of each biopsy, and complete blood count and serum biochemical analyses were performed. Attitude and appetite of all animals were evaluated daily. None of the animals developed clinically apparent adverse effects. A mild decrease in sorbitol dehydrogenase activity was detected in animals that underwent a single liver biopsy, and mild decreases in plasma protein and albumin concentrations were detected in animals that underwent multiple biopsies. Other significant changes were not detected. It is suggested that liver biopsy is safe in healthy llamas and alpacas and that, if necessary, multiple weekly liver biopsies can be performed safely in healthy alpacas.