Side chain cleavage of some steroid drug precursors by mycobacterium mutants
Patil, S.; Mishra, K.
Indian Journal of Experimental Biology 27(4): 374-375
1989
ISSN/ISBN: 0019-5189 Document Number: 510750
Cleavage of cholesterol, diosgenin and solasodine side chains by five Mycobacterium mutant strains to yield 17-ketosteroids was studied. Mycobacterium sp. NRRL B-3683 transformed cholesterol and diogenin to 17-ketosteroids up to 18.3 and 9.8% respectively, whereas 10.9% transformation of solasodine was obtained using Mycobacteirum sp. NRRL B-3805.
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