Lipoprotein (a) and the evaluation of low density cholesterol by the Friedewald formula: a new problem for an old equation
Hernández, C.; Chacón, P.; García-Pascual, L.; Rosselló, J.; Simó, R.
Medicina Clinica 113(8): 290-291
1999
ISSN/ISBN: 0025-7753 PMID: 10603581 Document Number: 510572
To evaluate the influence of lipoprotein(a) [Lp(a)] concentration on the LDL-cholesterol calculated by the Friedewald formula. Lp(a) was determined to a worker population of 947 subject in order to perform a correction of LDL-cholesterol obtained by the Friedewald formula. In subjects in whom Lp(a) was > 30 mg/dl (12.9%) LDL-cholesterol levels were overestimated 10 mg/dl at least. Lp(a) should be considered in order to reduce Friedewald's formula error on the estimation of LDL-cholesterol.