Use of serum cholesterol/triglyceride ratio to discern for which individuals the Friedewald formula can be used confidently
González Estrada, M.; Rodríguez Ferrer, C.R.; Astarloa, I.R.; Lahera, E.M.
Clinical Chemistry 36(9): 1673-1675
1990
ISSN/ISBN: 0009-9147 PMID: 2208709 Document Number: 363015
The values of low-density lipoprotein cholesterol obtained according to the Friedewald formula (Clin Chem 1972; 18:499-502), or by the De Long transformation (J Am Med Assoc 1986;256:2372-7), were compared with the values obtained when the individual cholesterol/triglyceride ratio of very-low-density lipoprotein was used for estimating the contribution of this lipoprotein to the total cholesterol. We found that these formulas gave the greatest errors for individuals with a low serum cholesterol/triglyceride ratio. We propose criteria for deciding when the numerically calculated value of low-density cholesterol is appropriate, and when it is not.