Influence of experimental diets on cholesterol and triglyceride levels of rabbit blood serum lipoproteins
Wehr, H.; Naruszewicz, M.; Nowicka, G.; Dziedziak, W.
Acta Physiologica Polonica 39(3): 202-206
1988
ISSN/ISBN: 0044-6033 PMID: 3227870 Document Number: 320296
Groups of rabbits were fed for six weeks various diets: standard diet + ethanol, high-cholesterol diet and a high-cholesterol + ethanol one. During the next six weeks every diet was supplemented with a fresh vegetable (carrot). Cholesterol and triglycerides were determined in the whole serum and in lipoprotein fractions. In rabbits fed standard diet ethanol caused a moderate elevation of VLDL cholesterol and triglyceride and LDL cholesterol levels. In animlas on high-cholesterol diet cholesterol and triglyceride concentrations in these fractions were very high. Simultaneous consumption of large amounts of cholesterol and of ethanol resulted in a greater rise of cholesterol concentration in the whole serum and in VLDL and LDL fraction than did high-cholesterol diet alone. Addition of carrot caused a pronounced reduction of serum cholesterol concentration in animals fed all kinds of diets. The reduction concerned mainly VLDL.