Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase
Hu, X.; Herzog, C.; Zimniak, P.; Singh, S.V.
Cancer Research 59(10): 2358-2362
1999
ISSN/ISBN: 0008-5472 PMID: 10344744 Document Number: 510563
The pi class glutathione S-transferase (GSTP1-1), which is polymorphic in human populations, is believed to play an important role in detoxification of the ultimate carcinogen of widespread environmental pollutant benzopyrene.
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