Exceptional mutagenicity of a benzo (a) pyrene diol epoxide in cultured mammalian cells
Newbold, R.F.; Brookes, P.
Nature 261(5555): 52-54
1976
ISSN/ISBN: 0028-0836 PMID: 1272374 Document Number: 105910
Document emailed within 1 workday
Related Documents
Ginsberg, G.L.; Atherholt, T.B. 1990: DNA adduct formation in mouse tissues in relation to serum levels of benzo(a)pyrene-diol-epoxide after injection of benzo(a)pyrene or the diol-epoxide Cancer Research 50(4): 1189-1194Wood, A.W.; Chang, R.L.; Huang, M.T.; Levin, W.; Lehr, R.E.; Kumar, S.; Thakker, D.R.; Yagi, H.; Jerina, D.M.; Conney, A.H. 1980: Mutagenicity of benzo(e)pyrene and triphenylene tetrahydroepoxides and diol-epoxides in bacterial and mammalian cells Cancer Research 40(6): 1985-1989
Wei, Q.; Gu, J.; Cheng, L.; Bondy, M.L.; Jiang, H.; Hong, W.K.; Spitz, M.R. 1996: Benzo(a)pyrene diol epoxide-induced chromosomal aberrations and risk of lung cancer Cancer Research 56(17): 3975-3979
Wislocki, P.G.; Wood, A.W.; Chang, R.L.; Levin, W.; Yagi, H.; Hernandez, O.; Dansette, P.M.; Herina, D.M.; Conney, A.H. 1976: Mutagenicity and cytotoxicity of benzo(a)pyrene arene oxides, phenols, quinones, and dihydrodiols in bacterial and mammalian cells Cancer Research 36(9 Pt.1): 3350-3357
Cerutti, P.A.; Sessions, F.; Hariharan, P.V.; Lusby, A. 1978: Repair of DNA damage induced by benzo(a)pyrene diol-epoxides i and Ii in human alveolar tumor cells Cancer Research 38(7): 2118-2124
Jiang, Y.-g.; Shen, Y.-l.; Fu, J.; Zhou, L.-l.; Cao, H. 2008: MicroRNA profiles of malignantly transformed cells induced by anti-benzo-a-pyrene-trans-7, 8-dihydrodiol-9, 10-epoxide Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 26(2): 81-85
Wood, A.W.; Wislocki, P.G.; Chang, R.L.; Levin, W.; Lu, A.Y.; Yagi, J.; Hernandez, O.; Herina, D.M.; Conney, A.H. 1976: Mutagenicity and cytotoxicity of benzo(a)pyrene benzo-ring epoxides Cancer Research 36(9 Pt.1): 3358-3366
Jiang, Y.; Chen, J.; Chen, X. 2001: Malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene metabolite dihydroxyepoxy benzo pyrene Wei Sheng Yan Jiu 30(3): 129-131
MacLeod, M.C.; Cohen, G.M.; Selkirk, J.K. 1979: Metabolism and macromolecular binding of the carcinogen benzo(a)pyrene and its relatively inert isomer benzo(e)pyrene by hamster embryo cells Cancer Research 39(9): 3463-3470
Ampy, F.R.; Saxena, S.; Verma, K. 1988: Mutagenicity of benzo(a)pyrene in uninduced tissues from BALB/c mice and Sprague-Dawley rats as an index of possible health risks using the Salmonella mutagenicity assay Cytobios 56(225): 81-87
Kumar, S.; Sikka, H.C.; Dubey, S.K.; Czech, A.; Geddie, N.; Wang, C.X.; LaVoie, E.J. 1989: Mutagenicity and tumorigenicity of dihydrodiols, diol epoxides, and other derivatives of benzo(f)quinoline and benzo(h)quinoline Cancer Research 49(1): 20-24
Glatt, H.; Piée, A.; Pauly, K.; Steinbrecher, T.; Schrode, R.; Oesch, F.; Seidel, A. 1991: Fjord- and bay-region diol-epoxides investigated for stability, SOS induction in Escherichia coli, and mutagenicity in Salmonella typhimurium and mammalian cells Cancer Research 51(6): 1659-1667
Hu, X.; Herzog, C.; Zimniak, P.; Singh, S.V. 1999: Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase Cancer Research 59(10): 2358-2362
Remsen, J.F.; Shireman, R.B. 1981: Effect of low-density lipoprotein on the incorporation of benzo(a)pyrene by cultured cells Cancer Research 41(8): 3179-3185
Bartholomew, J.C.; Pearlman, A.L.; Landolph, J.R.; Straub, K. 1979: Modulation of the cell cycle of cultured mouse liver cells by benzo(a)pyrene and its derivatives Cancer Research 39(7 Part 1): 2538-2543
Camalier, R.F.; Gantt, R.; Price, F.M.; Stephens, E.V.; Baeck, A.E.; Taylor, W.G.; Sanford, K.K. 1981: Effect of visible light on benzo(a)pyrene binding to DNA of cultured human skin epithelial cells Cancer Research 41(5): 1789-1793
Shen, A.L.; Fahl, W.E.; Wrighton, S.A.; Jefcoate, C.R. 1979: Inhibition of benzo(a)pyrene and benzo(a)pyrene 7,8-dihydrodiol metabolism by benzo(a)pyrene quinones Cancer Research 39(10): 4123-4129
Pontén, I.; Kim, S.K.; Gräslund, A.; Nordén, B.; Jernström, B. 1994: Synthesis and characterization of a (+)-anti-benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxide-oligonucleotide adduct Iarc Scientific Publications 1994(125): 433-436
Shuin, T.; Moriyama, M.; Nishimura, R.; Takai, S.; Umeda, M. 1981: Studies on the cytotoxicity, mutagenicity and chromosomal aberration-inducing activity of aclacinomycin A in cultured mammalian cells Gan 72(2): 197-204
Thakker, D.R.; Levin, W.; Buening, M.; Yagi, H.; Lehr, R.E.; Wood, A.W.; Conney, A.H.; Jerina, D.M. 1981: Species-specific enhancement by 7,8-benzoflavone of hepatic microsomal metabolism of benzo[e]pyrene 9,10-dihydrodiol to bay-region diol epoxides Cancer Research 41(4): 1389-1396