Computer analysis of regulatory signals in complete bacterial genomes. Participation of ribosome binding

Mironov, A.A.; Frishman, D.; Gelfand, M.S.

Molekuliarnaia Biologiia 33(1): 133-140

1999


ISSN/ISBN: 0026-8984
PMID: 10330671
Document Number: 509741
An algorithm of precise mapping of gene terminals in completely sequenced bacterial genomes is proposed. As opposed to the existing algorithms, the new algorithm does not need a tutorial and does not use homology analysis. The results are presented on testing the algorithm in Escherichia coli, Haemophilus influenzae, Helicobacter pylori, Bacillus subtilis, Methanococcus jannaschii, Archaeglobus fulgidus, and Methanobacterium thermoautotrophicum genomes. Reliability of the existing annotations of complete bacterial genomes is discussed.

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