Neck lymph node metastases of unknown origin: nasopharyngeal origin and EBV (Epstein-Barr virus)
Plaza, G.; Santón, A.; Fogué, L.; Bellas, C.; Martínez Vidal, A.
Acta Otorrinolaringologica Espanola 50(8): 623-629
1999
ISSN/ISBN: 0001-6519 PMID: 10619898 Document Number: 508478
We present a retrospective series of 16 cases of undifferentiated squamous carcinoma in cervical metastatic nodes of unknown primary. We review their clinical and radiological evaluation in search of a possible primary tumor, their response to treatment and the eventual development of a primary tumor. Furthermore, we study the presence of Epstein-Barr virus in the metastases as a predictor of their nasopharyngeal origin, in relation to the finding of primary lesions in the nasopharynx during further follow-up of the cases.