The effect of x-ray contrast media on the concentration of intracellular calcium in mononuclear cells
Shabunin, I.V.; Shimanovskiĭ, N.L.; Panov, V.O.; Kalinina, A.A.; Sviridov, N.K.
Eksperimental'naia i Klinicheskaia Farmakologiia 62(6): 62-65
1999
ISSN/ISBN: 0869-2092 PMID: 10650532 Document Number: 508473
It was shown by the method of fluorescent probes that iodine-containing radiocontrast agents Triombrast > Omnipaque > Ultravist > Melitrast increase the content of intracellular Ca2+ in macrophages of the abdominal cavity of rats. Increase in the entry of Ca2+ from the external environment is the main factor of the change in the intracellular concentration of Ca2+ ions in the macrophages in interaction with radiocontrast agents.