Effect of intravenous contrast media used in urography on the complement system and blood calcium

Korzec-Grzegorczyk, I.

Polski Tygodnik Lekarski 44(36-39): 830-833

1989


ISSN/ISBN: 0032-3756
PMID: 2486515
Document Number: 327901
The investigations were carried out in 30 persons subjected to the urography, in which influence of intravenous contrast media on coagulation and fibrinolysis system were studied (Part I). In venous blood collected before and in determined time intervals after injection of "Uropolinum" Polfa hemolytic activity of the complement system, concentration of its components (C3, C4) and total calcium level in blood were assayed. These parameters may contribute to the pathogenesis of side effects following injection of the contrast media. Disturbances in function of coagulation system were accompanied by a decrease in calcium level and activity of the complement. This phenomenon did not correlate with clinical symptoms.

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