Distal myasthenia gravis
Nations, S.P.; Wolfe, G.I.; Amato, A.A.; Jackson, C.E.; Bryan, W.W.; Barohn, R.J.
Neurology 52(3): 632-634
1999
ISSN/ISBN: 0028-3878 PMID: 10025802 Document Number: 507776
Myasthenia gravis (MG) characteristically involves ocular, bulbar, and proximal extremity muscles. Distal extremity muscles are typically spared or less prominently involved. The authors performed a retrospective chart review of MG patients treated at two university-based neuromuscular clinics. From a total population of 236, nine patients (3%) had distal extremity weakness exceeding proximal weakness by at least one Medical Research Council grade during their illness. Hand muscles, particularly finger extensors, were involved more frequently than were distal leg and foot muscles.