A study of clinicopathology and lectin immunohistochemistry in unicystic ameloblastoma
Wang, Y.; Wang, S.; Chen, X.
Zhonghua Kou Qiang Yi Xue Za Zhi 34(4): 226-228
1999
ISSN/ISBN: 1002-0098 PMID: 11776912 Document Number: 505396
To investigate clinicopathological characteristics of unicystic ameloblastoma and histological markers for differential diagnosis with odontogenic cyst. HE staining and histopathological observation, and lectin UEA-1, BSA-1 immunohistochemistry staining. 40 cases of unicystic ameloblastoma were divided histologically into 3 groups. In odontogenic cysts, most of epithelial lining showed positive binding with UEA-1 and BSA-1, whereas negative reactions were obtained for these two lectins in the epithelial components of unicystic ameloblastoma and solid or multicystic ameloblastoma, except for limited UEA-1 or BSA-1 binding to markedly keratinized tumor cells in several cases of ameloblastomas. The unicystic ameloblastoma is a distinct entity which has characteristic clinicopathology. The lectin staining for UEA-1 and BSA-1 is a useful histological aid to differential diagnosis between unicystic ameloblastoma and odontogenic cyst.