Immunohistochemistry applied to the study of bone marrow Gaucher's cells: a case report
Alterini, R.; Rigacci, L.; Stefanacci, S.; Innocenti, F.; Santini, V.; Carrai, V.; Rossi Ferrini, P.
European Journal of Histochemistry Ejh 43(3): 235-239
1999
ISSN/ISBN: 1121-760X PMID: 10563256 Document Number: 499297
Gaucher's disease is frequently associated with immunologic abnormalities, e.g. hypergammaglobulinemia, polyclonal gammopathy and benign monoclonal gammopathy. A patient with Gaucher's disease and a selective accumulation of IgM k in Gaucher's cells without serum monoclonal gammopathies is described. The selective accumulation is detected by immunohistochemistry analysis performed on cryostat bone marrow biopsies.
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