The clinico-morphological characteristics of salmonellosis typhimurium in children
Nezhoda, I.I.
Likars'ka Sprava 1: 101-103
1999
ISSN/ISBN: 1019-5297 PMID: 10424015 Document Number: 498663
Clinical and morphological features were studied of the course of gastrointestinal and generalized forms of salmonellosis. The grave gastrointestinal form runs its course against the unfavourable premorbid background getting associated with other flora: Proteus, Citrobacter, Klebsiella, Staphylococcus aureus. A distinguishing feature of the generalized form is its variegated clinical symptomatology. Noted in some instances is an acute onset of the illness with a clinical picture of purulent meningitis, but it happens that it runs a little-by-little, and a wave-like course presenting with poorly manifest phenomena of gastroenteritis and subsequent development of meningitis. Morphological changes in Salmonella enterocolitis are characterized by macrophagal infiltration of the mucosal lamina proper and by disordered hemomicrocirculation in postcapillaries and venules. The generalized form is associated with profound irreversible processes in the brain, liver, kidneys, and myocardium.