The correction of the increased blood viscosity syndrome in brain ischemia in rats with a combination of dikvertin and ascorbic acid
Plotnikov, M.B.; Aliev, O.I.; Maslov, M.Iu.; Vasil'ev, A.S.; Tiukavkina, N.A.
Eksperimental'naia i Klinicheskaia Farmakologiia 62(6): 45-47
1999
ISSN/ISBN: 0869-2092 PMID: 10650527 Document Number: 498089
In experiments in vitro on a model of the syndrome of increased blood viscosity dikvertin reduced blood viscosity, weakened aggregation of red cells and raised their property of becoming distorted. A mixture of dikvertin and ascorbic acid improved the hemorrheologic parameters better than do dikvertin and tanakan. On a model of chronic ischemia of the brain of rats attended with deterioration of blood rheologic parameters, it was demonstrated that a course of treatment with a dikvertin and ascorbic acid complex decreases the manifestations of the syndrome of increased blood viscosity.