Osmotic fragility test of erythrocytes with a coil planet centrifuge
Kogawa, H.; Yabushita, N.; Kageyama, K.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 192(5): 997-1006
1998
ISSN/ISBN: 0037-9026 PMID: 9871811 Document Number: 497617
The measurement of osmotic fragility of erythrocytes has been applied to the diagnosis of hemolytic diseases, studies of membrane permeability and alternations leading to destruction of erythrocytes. Almost 30 years have gone by since the coil planet centrifuge system was devised for measuring the osmotic fragility of erythrocytes. Many excellent studies by means of this centrifuge system have been published. Prominent investigations are reviewed as follows: in relation to the osmotic fragility, various liver diseases, angina pectoris, trapping the aged erythrocytes, tumor, lactic acid, unsaturated fatty acids, free cholesterol, exercise and lead exposure level were examined.