Experimental study of the biopreparation Lymphotilin as an antiproliferative and antitumor agent
Tiagotin, I.V.; Polotskiĭ, A.E.; Vakhitov, T.I.; Tutova, I.I.; Rybakova, L.P.
Voprosy Onkologii 44(1): 92-96
1998
ISSN/ISBN: 0507-3758 PMID: 9578739 Document Number: 496377
We found in experiments involving the use of a biopreparation lymphotilin that its administration was followed by a decrease in proliferative activity of cultured tumor cells and a longer survival of mice bearing transplantable leukemia. An intensified intercalation of ethidium bromide in nucleic acids of tumor cells in lymphotilin culture points to the drug activity on nuclear level. Tumor cell inhibition by lymphotilin holds much promise for the practice of hematology.