Chemical imaging of nucleic acids, proteins and lipids of a single living cell. Application of synchrotron infrared microspectrometry in cell biology
Jamin, N.; Dumas, P.; Moncuit, J.; Fridman, W.H.; Teillaud, J.L.; Carr, G.L.; Williams, G.P.
Cellular and Molecular Biology 44(1): 9-13
1998
ISSN/ISBN: 0145-5680 PMID: 9551633 Document Number: 495891
Hybridoma B-cells have been used as models to evaluate the performance of synchrotron infrared microscopy to obtain chemical images of a single living cell. Chemical mapping of nucleic acids, proteins and lipids at a resolution of a few microns, close to the diffraction limit in the mid-infrared region are shown.